EP300 / Unconjugated / 7D8A6

Product Details
Supplier Biorbyt
Catalog #: orb69111 (View supplier product page)
Size 100 ul
Price $567.80
Antigen EP300
Clone 7D8A6
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications ELISA, FC, ICC, IF, IHC-P, WB
Description Mouse monoclonal antibody to EP300
About EP300 and Purified
EP300 This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra