CD148 / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb726861 (View supplier product page)
Size 100 ul
Price $598.40
Antigen CD148
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications
Description Rabbit polyclonal antibody against DEP1 conjugated to Biotin
About CD148 and Biotin
CD148 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Biotin Excitation and Emission Spectra