CSE1L / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb719444 (View supplier product page)
Size 100 ul
Price $598.40
Antigen CSE1L
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human, Rat
Applications
Description Rabbit polyclonal antibody against CSE1L conjugated to Biotin
About CSE1L and Biotin
CSE1L Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
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Biotin Excitation and Emission Spectra