CYSLTR2 / FITC /

Product Details
Supplier Biorbyt
Catalog #: orb462901 (View supplier product page)
Size 100 ug
Price $567.80
Antigen CYSLTR2
Clone
Host Rabbit
Isotype IgG
Conjugate FITC
Target Species Mouse, Rat
Applications ICC, IF
Description Rabbit polyclonal antibody against CysLT2 conjugated to FITC -
About CYSLTR2 and FITC
CYSLTR2 The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008]
FITC Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

FITC Excitation and Emission Spectra