MAP3K8 / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb38770 (View supplier product page)
Size 400 ul
Price $625.60
Antigen MAP3K8
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC-P, WB
Description Purified rabbit polyclonal antibody.
About MAP3K8 and Purified
MAP3K8 This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]
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Purified Excitation and Emission Spectra