Caspase 3 / CF405M /

Product Details
Supplier Biorbyt
Catalog #: orb625436-CF405M (View supplier product page)
Size 100 ug
Price $452.20
Antigen Caspase 3
Clone
Host Rabbit
Isotype IgG
Conjugate CF405M
Target Species Human, Mouse, Rat
Applications ICC, IF
Description Rabbit polyclonal antibody to Caspase 3 -
About Caspase 3 and CF405M
Caspase 3 The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
CF405M CF®405M from Biotium is a fluorophore with an excitation peak at 408 nm and an emission peak at 452 nm. It is spectrally similar to Pacific Blue, V450 and DY-415. It can be use in fluorescence microscopy and flow cytometry. Specifically, it has been validated for use in STED, Structured Illumination (SIM) and 2-Photon microscopy. In flow cytometry, superior alternatives are Brilliant™ Violet 480, Brilliant™ Violet 510 and StarBright Violet 515.
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CF405M Excitation and Emission Spectra