CARD11 / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb649215-50ul (View supplier product page)
Size 50 μl
Price $425.00
Antigen CARD11
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications IF, IHC-P, WB
Description Rabbit polyclonal antibody to CARD11
About CARD11 and Purified
CARD11 The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra