BLNK / HRP /

Product Details
Supplier Biorbyt
Catalog #: orb469267 (View supplier product page)
Size 100 ug
Price $567.80
Antigen BLNK
Clone
Host Rabbit
Isotype IgG
Conjugate HRP
Target Species Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Description Rabbit polyclonal antibody against BLNK conjugated to HRP -
About BLNK and HRP
BLNK This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
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HRP Excitation and Emission Spectra