Bestrophin 1 / Unconjugated /
Bestrophin 1 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb648759-50ul (View supplier product page) | |
| Size | 50 μl | |
| Price | $425.00 | |
| Antigen | Bestrophin 1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse, Rat | |
| Applications | IHC-P, WB | |
| Description | Rabbit polyclonal antibody to BEST1 |
About Bestrophin 1 and Purified
| Bestrophin 1 | This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008] |
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Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$425.00
Supplier Page
Supplier Page
