ACLY / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb676592-50ul (View supplier product page)
Size 50 μl
Price $459.00
Antigen ACLY
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications ELISA, IF, WB
Description Rabbit polyclonal antibody to ACLY
About ACLY and Purified
ACLY ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra