Cadherin-16 / DyLight 488 / CDH16/2448

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08959G (View supplier product page)
Size 100 ul
Price $519.00
Antigen Cadherin-16
Clone CDH16/2448
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 488
Target Species Human
Applications ELISA, IHC, IHC-P
Description Cadherin-16 Antibody (CDH16/2448) [DyLight 488]
About Cadherin-16 and DyLight 488
Cadherin-16 This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra