ErbB4 / Alexa Fluor 405 / HFR-1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08902AF405 (View supplier product page)
Size 100 ul
Price $519.00
Antigen ErbB4
Clone HFR-1
Host Mouse
Isotype IgG2b κ
Conjugate Alexa Fluor 405
Target Species Human, Mouse
Applications FC, ICC/IF
Description ErbB4/Her4 Antibody (HFR-1) [Alexa Fluor 405]
About ErbB4 and Alexa Fluor 405
ErbB4 This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra