Cadherin-16 / Alexa Fluor 488 / rCDH16/1071

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08881AF488 (View supplier product page)
Size 100 ul
Price $519.00
Antigen Cadherin-16
Clone rCDH16/1071
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 488
Target Species Canine, Human, Mouse, Rabbit, Rat
Applications WB, FC, IHC, IHC-P
Description Cadherin-16 Antibody (rCDH16/1071) [Alexa Fluor 488]
About Cadherin-16 and Alexa Fluor 488
Cadherin-16 This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra