CD220 / Alexa Fluor 750 / INSR/2277R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08838AF750 (View supplier product page)
Size 100 ul
Price $519.00
Antigen CD220
Clone INSR/2277R
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 750
Target Species Human
Applications IHC, IHC-P
Description Insulin R/CD220 Antibody (INSR/2277R) [Alexa Fluor 750]
About CD220 and Alexa Fluor 750
CD220 This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Alexa Fluor 750 Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications.
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Alexa Fluor 750 Excitation and Emission Spectra