Bcl-6 / DyLight 350 / rBCL6/1527

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08779UV (View supplier product page)
Size 100 ul
Price $449.00
Antigen Bcl-6
Clone rBCL6/1527
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 350
Target Species Human
Applications IHC, IHC-P
Description Bcl-6 Antibody (rBCL6/1527) [DyLight 350]
About Bcl-6 and DyLight 350
Bcl-6 The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra