Bcl-6 / Alexa Fluor 647 / rBCL6/1527

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08779AF647 (View supplier product page)
Size 100 ul
Price $449.00
Antigen Bcl-6
Clone rBCL6/1527
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 647
Target Species Human
Applications IHC, IHC-P
Description Bcl-6 Antibody (rBCL6/1527) [Alexa Fluor 647]
About Bcl-6 and Alexa Fluor 647
Bcl-6 The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra