Spastin / Alexa Fluor 405 / Sp 6C6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08753AF405 (View supplier product page)
Size 100 ul
Price $519.00
Antigen Spastin
Clone Sp 6C6
Host Mouse
Isotype IgG2a κ
Conjugate Alexa Fluor 405
Target Species Human, Mouse, Rat
Applications WB, ICC/IF
Description Spastin Antibody (Sp 6C6) [Alexa Fluor 405]
About Spastin and Alexa Fluor 405
Spastin This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The use of alternative translational initiation sites in this gene results in a single transcript variant that can produce isoforms that differ in the length of their N-terminus and which thereby differ in the efficiency of their export from the nucleus to the cytoplasm. In addition, alternative splicing results in multiple transcript variants that encode isoforms that differ in other protein regions as well. One isoform of this gene has been shown to be a microtubule-severing enzyme that regulates microtubule abundance, mobility, and plus-end distribution. Mutations in this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq, May 2018]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Alexa Fluor 405 Excitation and Emission Spectra