DAZL / Alexa Fluor 488 / DAZL/4253

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08742AF488 (View supplier product page)
Size 100 ul
Price $519.00
Antigen DAZL
Clone DAZL/4253
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 488
Target Species Cynomolgus macaque, Human, Mouse, Rat
Applications WB, IHC, ICC/IF
Description DAZL Antibody (DAZL/4253) [Alexa Fluor 488]
About DAZL and Alexa Fluor 488
DAZL The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra