SET / Alexa Fluor 405 / PCRP-SET-1C6

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08730AF405 (View supplier product page)
Size 100 ul
Price $519.00
Antigen SET
Clone PCRP-SET-1C6
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, FC, ICC/IF
Description SET Antibody (PCRP-SET-1C6) [Alexa Fluor 405]
About SET and Alexa Fluor 405
SET The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra