ATRX / DyLight 680 / rATRX/3446

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08673FR (View supplier product page)
Size 100 ul
Price $519.00
Antigen ATRX
Clone rATRX/3446
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 680
Target Species Human
Applications IHC, IHC-P
Description ATRX Antibody (rATRX/3446) [DyLight 680]
About ATRX and DyLight 680
ATRX The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2017]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra