SREBP1 / DyLight 680 / SREBP1/1578

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08432FR (View supplier product page)
Size 100 ul
Price $519.00
Antigen SREBP1
Clone SREBP1/1578
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 680
Target Species Human
Applications ELISA
Description SREBP1 Antibody (SREBP1/1578) [DyLight 680]
About SREBP1 and DyLight 680
SREBP1 This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra