MCM7 / DyLight 680 / MCM7/2832R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08405FR (View supplier product page)
Size 100 ul
Price $519.00
Antigen MCM7
Clone MCM7/2832R
Host Rabbit
Isotype IgG
Conjugate DyLight 680
Target Species Human
Applications WB, IHC, IHC-P
Description MCM7 Antibody (MCM7/2832R) [DyLight 680]
About MCM7 and DyLight 680
MCM7 The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra