APE1 / Unconjugated / CPTC-APEX1-2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08370 (View supplier product page)
Size 100 ug
Price $519.00
Antigen APE1
Clone CPTC-APEX1-2
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Human
Applications WB, FC, IHC, ICC/IF, IHC-P, Protein Array
Description APE Antibody (CPTC-APEX1-2) - Azide and BSA Free
About APE1 and Purified
APE1 The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.[provided by RefSeq, Dec 2019]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra