Filaggrin / Alexa Fluor 647 / FLG/1945

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08355AF647 (View supplier product page)
Size 100 ul
Price $519.00
Antigen Filaggrin
Clone FLG/1945
Host Mouse
Isotype IgG2b κ
Conjugate Alexa Fluor 647
Target Species Human
Applications IHC, IHC-P
Description Filaggrin Antibody (FLG/1945) [Alexa Fluor 647]
About Filaggrin and Alexa Fluor 647
Filaggrin The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra