GAD1 / DyLight 550 / GAD1/2391

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08276R (View supplier product page)
Size 100 ul
Price $519.00
Antigen GAD1
Clone GAD1/2391
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 550
Target Species Human
Applications WB, ELISA, IHC, IHC-P
Description GAD1/GAD67 Antibody (GAD1/2391) [DyLight 550]
About GAD1 and DyLight 550
GAD1 This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq, Jul 2008]
DyLight 550 DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 550 Excitation and Emission Spectra