CD8b / Alexa Fluor 750 / H35-17.2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08222AF750 (View supplier product page)
Size 100 ul
Price $519.00
Antigen CD8b
Clone H35-17.2
Host Rat
Isotype IgG2b κ
Conjugate Alexa Fluor 750
Target Species Mouse
Applications FC, ICC/IF
Description CD8 beta Antibody (H35-17.2) [Alexa Fluor 750]
About CD8b and Alexa Fluor 750
CD8b The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
Alexa Fluor 750 Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Alexa Fluor 750 Excitation and Emission Spectra