ASIC1 / ATTO 390 / S271-44

Product Details
Supplier Biorbyt
Catalog #: orb150276 (View supplier product page)
Size 100 ug
Price $647.70
Antigen ASIC1
Clone S271-44
Host Mouse
Isotype IgG1
Conjugate ATTO 390
Target Species Human, Mouse, Rat
Applications ICC, WB, IHC
Description Mouse monoclonal to ASIC1 (ATTO-390). Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4. 3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety.. -
About ASIC1 and ATTO 390
ASIC1 This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
ATTO 390 ATTO 390 from ATTO-TEC has an excitation peak at 390 nm and an emission peak at 448 nm. It is a novel fluorescent label with a coumarin structure. Characteristic features of the label are high fluorescence quantum yield, large Stokes-shift, good photo-stability, and low molecular weight.
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ATTO 390 Excitation and Emission Spectra