APC / CF647 /

Product Details
Supplier Biorbyt
Catalog #: orb213564-CF647 (View supplier product page)
Size 100 &mu
Price $448.80
Antigen APC
Clone
Host Rabbit
Isotype IgG
Conjugate CF647
Target Species Human, Rat
Applications ICC, IF
Description Rabbit polyclonal antibody to APC
About APC and CF647
APC This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Dec 2019]
CF647 CF®647 from Biotium is a fluorophore with an excitation peak at 642 nm and an emission peak at 662 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 647, DyLight™ 649 and Cy5.
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CF647 Excitation and Emission Spectra