alpha 2 Macroglobulin / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb720004 (View supplier product page)
Size 100 ul
Price $598.40
Antigen alpha 2 Macroglobulin
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human
Applications
Description Rabbit polyclonal antibody against alpha 2 Macroglobulin conjugated to Biotin
About alpha 2 Macroglobulin and Biotin
alpha 2 Macroglobulin The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
Citations
Additional
Sources
Reviews & Ratings
Biotin Excitation and Emission Spectra