CD2 / Vio Bright 515 / REA972

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-116-257 (View supplier product page)
Size 30 tests in 60 µL
Price $180.00
Antigen CD2
Clone REA972
Host Human
Isotype IgG1
Conjugate Vio Bright 515
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
Description Clone REA972 recognizes the human CD2 antigen, a 50 kDa single-chain transmembrane glycoprotein also known as LFA-2 or receptor for sheep erythrocytes. CD2 functions as a costimulatory molecule on T and natural killer (NK) cells and is a receptor for other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58). It belongs to the Ig superfamily and is involved in cell signaling and lymphocyte adhesion. The CD2 antibody reacts with 80–90% of peripheral blood lymphocytes and more than 95% of thymocytes and recognizes all T cells and a subset of NK cells. | Additional information: Clone REA972 displays negligible binding to Fc receptors.
About CD2 and Vio Bright 515
CD2 The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]
Vio Bright 515 Vio®Bright® B515 from Miltenyi has an excitation peak at 488 nm and an emission peak at 514. It is comparable to BB515 in flow cytometry.
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Vio Bright 515 Excitation and Emission Spectra