IL-21 R / Oligo / 17A12

Product Details
Supplier BioLegend
Catalog #: 359519 (View supplier product page)
Size 10UG
Price $369.00
Antigen IL-21 R
Clone 17A12
Host Mouse
Isotype IgG1 κ
Conjugate Oligo
Target Species Human
Applications Proteogenomics
Description TotalSeq-A0985 anti-human CD360 (IL-21R)
About IL-21 R and Oligo
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Oligo Excitation and Emission Spectra