CD130 / Oligo / 2E1B02

Product Details
Supplier BioLegend
Catalog #: 362013 (View supplier product page)
Size 10UG
Price $369.00
Antigen CD130
Clone 2E1B02
Host Mouse
Isotype IgG2a κ
Conjugate Oligo
Target Species Human
Applications Proteogenomics
Description TotalSeq-B0820 anti-human CD130 (gp130)
About CD130 and Oligo
CD130 The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
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Oligo Excitation and Emission Spectra