CD62L / Brilliant Ultraviolet 563 / MEL-14

Citations: (3)
Product Details
Supplier BD Biosciences
Catalog #: 741230 (View supplier product page)
Size 50 μg
Price $386.00
Antigen CD62L
Clone MEL-14
Host Rat
Isotype IgG2a κ
Conjugate Brilliant Ultraviolet 563
Target Species Mouse
Applications FC
Description Ms CD62L BUV563 MEL-14 50ug
About CD62L and Brilliant Ultraviolet 563
CD62L This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Brilliant Ultraviolet 563 Brilliant™ UltraViolet 563 (BUV563) is a green-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 585/15 bandpass filter. BUV563 has an excitation peak at 348 nm and an emission peak at 563 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 563 Excitation and Emission Spectra