PI3K C2 beta / HRP / OTI3B1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-73395H (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen PI3K C2 beta
Clone OTI3B1
Host Mouse
Isotype IgG1
Conjugate HRP
Target Species Human
Applications WB, IHC
Description PI 3-Kinase C2 beta Antibody (OTI3B1) [HRP]
About PI3K C2 beta and HRP
PI3K C2 beta The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008]
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HRP Excitation and Emission Spectra