SLC12A1 / DyLight 488 /
SLC12A1 / DyLight 488 /
Product Details
| Supplier | Novus Biologicals, a Bio-Techne brand | |
|---|---|---|
| Catalog #: | NBP2-98480G (View supplier product page) | |
| Size | 0.1 ml | |
| Price | $369.00 | |
| Antigen | SLC12A1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | DyLight 488 | |
| Target Species | Human | |
| Applications | IHC, IHC-P | |
| Description | NKCC2/SLC12A1 Antibody [DyLight 488] |
About SLC12A1 and DyLight 488
| SLC12A1 | This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
DyLight 488 Excitation and Emission Spectra
$369.00
Supplier Page
Supplier Page
