LIF R alpha / DyLight 755 / 1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-89586IR (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen LIF R alpha
Clone 1
Host Rabbit
Isotype IgG
Conjugate DyLight 755
Target Species Human
Applications ELISA, IHC, IHC-P
Description LIFR alpha Antibody (001) [DyLight 755]
About LIF R alpha and DyLight 755
LIF R alpha This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra