CD268 / Red 718 / 11C1

Product Details
Supplier BD Biosciences
Catalog #: 751971 (View supplier product page)
Size 50 μg
Price $400.00
Antigen CD268
Clone 11C1
Host Mouse
Isotype IgG1 κ
Conjugate Red 718
Target Species Human
Applications FC
Description Hu CD268 (BAFF Receptor) R718 11C1 50ug
About CD268 and Red 718
CD268 B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
Red 718 Red 718 is excited by the 640 laser and emission captured by the 695/40 filter. It can be used with the following analysis platforms: Flow Cytometry.
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Red 718 Excitation and Emission Spectra