SELENOH / Unconjugated /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-14637-25ul (View supplier product page)
Size 25ul
Price $329.00
Antigen SELENOH
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC, ICC/IF, IHC-P
Description SELH Antibody
About SELENOH and Purified
SELENOH This gene encodes a nucleolar protein, which belongs to the SelWTH family. It functions as an oxidoreductase, and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways, promote mitochondrial biogenesis and mitochondrial function, and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2016]
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Purified Excitation and Emission Spectra