Cdk6 / DyLight 680 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-98990FR (View supplier product page)
Size 0.1 ml
Price $369.00
Antigen Cdk6
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 680
Target Species Human
Applications IHC, IHC-P
About Cdk6 and DyLight 680
Cdk6 The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly. [provided by RefSeq, Aug 2017]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra