PKN1 / DyLight 755 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-98761IR (View supplier product page)
Size 0.1 ml
Price $369.00
Antigen PKN1
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 755
Target Species Human
Applications WB, ICC/IF
About PKN1 and DyLight 755
PKN1 The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra