ATP7b / Alexa Fluor 647 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-98188AF647 (View supplier product page)
Size 0.1 ml
Price $369.00
Antigen ATP7b
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 647
Target Species Human
Applications IHC, IHC-P
About ATP7b and Alexa Fluor 647
ATP7b This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Alexa Fluor 647 Excitation and Emission Spectra