ATP7b / Alexa Fluor 405 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-98188AF405 (View supplier product page)
Size 0.1 ml
Price $369.00
Antigen ATP7b
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 405
Target Species Human
Applications IHC, IHC-P
About ATP7b and Alexa Fluor 405
ATP7b This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. [provided by RefSeq, Dec 2019]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra