Plakophilin 1 / Alexa Fluor 488 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-97275AF488 (View supplier product page)
Size 0.1 ml
Price $356.00
Antigen Plakophilin 1
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Human
Applications IHC, IHC-P
About Plakophilin 1 and Alexa Fluor 488
Plakophilin 1 This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra