p53 / CF660R / PCRP-TP53-1F7

Product Details
Supplier Biotium
Catalog #: BNC611925-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen p53
Clone PCRP-TP53-1F7
Host Mouse
Isotype IgG1
Conjugate CF660R
Target Species Human
Applications IHC-P
Description p53 Tumor Suppressor Monoclonal Mouse Antibody (PCRP-TP53-1F7)
About p53 and CF660R
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
CF660R CF®660R from Biotium is a fluorophore with an excitation peak at 662 nm and an emission peak at 682 nm. It can be useful in both fluorescence microscopy and flow cytometry. It is spectrally similar to Alexa Fluor™ 660.
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CF660R Excitation and Emission Spectra