alpha-Methylacyl-CoA Racemase / CF770 / AMACR/2748R

Product Details
Supplier Biotium
Catalog #: BNC702748-500 (View supplier product page)
Size 500 μl
Price $459.00
Antigen alpha-Methylacyl-CoA Racemase
Clone AMACR/2748R
Host Rabbit
Isotype IgG
Conjugate CF770
Target Species Human
Applications IHC-P
Description AMACR / p504S Recombinant Monoclonal Rabbit Antibody (AMACR/2748R)
About alpha-Methylacyl-CoA Racemase and CF770
alpha-Methylacyl-CoA Racemase This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
CF770 CF®770 from Biotium is a fluorophore with an excitation peak at 770 nm and an emission peak at 797 nm. It is spectrally similar to DyeLight 800 and IRDye® 800CW.
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CF770 Excitation and Emission Spectra