CD68 / CF770 / LAMP4/1830

Product Details
Supplier Biotium
Catalog #: BNC701830-500 (View supplier product page)
Size 500 μl
Price $470.00
Antigen CD68
Clone LAMP4/1830
Host Mouse
Isotype IgG2b κ
Conjugate CF770
Target Species Human
Applications IF, IHC-P, FC, WB
Description CD68 Monoclonal Mouse Antibody (LAMP4/1830)
About CD68 and CF770
CD68 This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
CF770 CF®770 from Biotium is a fluorophore with an excitation peak at 770 nm and an emission peak at 797 nm. It is spectrally similar to DyeLight 800 and IRDye® 800CW.
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CF770 Excitation and Emission Spectra