Perforin / CF543 / PRF1/2468

Product Details
Supplier Biotium
Catalog #: BNC432468-100 (View supplier product page)
Size 100 μl
Price $170.00
Antigen Perforin
Clone PRF1/2468
Host Mouse
Isotype IgG2b κ
Conjugate CF543
Target Species Human
Applications IHC-P
Description Perforin-1 Monoclonal Mouse Antibody (PRF1/2468)
About Perforin and CF543
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
CF543 CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry.
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CF543 Excitation and Emission Spectra