Bcl-6 / CF543 / rBCL6/1527

Product Details
Supplier Biotium
Catalog #: BNC431950-100 (View supplier product page)
Size 100 μl
Price $170.00
Antigen Bcl-6
Clone rBCL6/1527
Host Mouse
Isotype IgG1 κ
Conjugate CF543
Target Species Human
Applications IHC-P
Description Bcl-6 Recombinant Monoclonal Mouse Antibody (rBCL6/1527)
About Bcl-6 and CF543
Bcl-6 The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
CF543 CF®543 from Biotium is a fluorophore with an excitation peak at 541 nm and an emission peak at 560 nm. It can be useful in both fluorescence microscopy and flow cytometry.
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CF543 Excitation and Emission Spectra