GFAP / Biotin / rASTRO/789

Product Details
Supplier Biotium
Catalog #: BNCB2227-500 (View supplier product page)
Size 500 μl
Price $551.00
Antigen GFAP
Clone rASTRO/789
Host Mouse
Isotype IgG1
Conjugate Biotin
Target Species Bovine, Chicken, Human, Mouse, Porcine, Rabbit, Rat
Applications FC, ICS, IHC, IHC-P, WB
Description This MAb recognizes a protein of ~50 kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
About GFAP and Biotin
GFAP This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
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Biotin Excitation and Emission Spectra