CD53 / DyLight 405 / 4

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90697V (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CD53
Clone 4
Host Rabbit
Isotype IgG
Conjugate DyLight 405
Target Species Mouse
Applications WB, IF
Description Rabbit CD53 antibody [DyLight 405] detects Mouse
About CD53 and DyLight 405
CD53 The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra